PRP vs. PRF: What's the Difference and Which Works Better?

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Dr. Vu Ho

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1/13/2026

Are you considering regenerative treatments but unsure whether PRP or PRF is better? While both options are useful when it comes to skin rejuvenation or advanced hair restoration, PRF contains a higher concentration of growth factors and releases them more slowly, often making it more effective for certain applications. 

 At Beyond Beautiful in Plano, Dr. Vu Ho, a board-certified facial plastic surgeon, and Dr. Jeffrey Caruth, a cosmetic surgeon, serve patients from McKinney, Frisco, Prosper, Solano, Allen, and Richardson, TX. If you want to learn which option is right for you, call now to schedule a consultation. 

How does PRP work? 

So, how does PRP work? PRP stands for platelet-rich plasma, a concentrated solution derived from your blood. Platelets contain growth factors that support natural healing and tissue regeneration. When carefully injected into the skin or scalp, PRP encourages new cell growth and improves texture and tone. 

PRP is used for a wide range of cosmetic issues and can even act as a collagen booster. Because it comes from your own body, there's almost no risk of allergic reaction. The treatment is also minimally invasive, making it a convenient option for patients looking to refresh their appearance or stimulate hair growth. 

What is PRF? 

So, what is PRF, and how is it different? PRF stands for platelet-rich fibrin, a more advanced version of PRP. Like PRP, it's derived from your blood, but the processing method is different. PRF is created without anticoagulants, which allows it to form a fibrin matrix that traps more growth factors. This fibrin structure gradually releases the growth factors, which may provide longer-lasting benefits. 

Additionally, PRF is often considered a superior collagen booster because of its higher concentration of healing components. This makes it particularly effective for patients seeking deeper tissue repair. 

Key differences between PRP and PRF 

While both treatments use your blood to promote healing, there are several key differences between the two:  

  • Composition: PRF contains more growth factors than PRP. 
  • Release of growth factors: PRP releases growth factors quickly, while PRF releases them gradually over time. 
  • Results: PRF often provides longer-lasting and more dramatic results due to its sustained release and higher concentration. 

At Beyond Beautiful in Plano, Dr. Ho and Dr. Caruth evaluate your goals and recommend the treatment that fits your needs, whether you're seeking skin rejuvenation or advanced hair restoration. 

What to expect during treatment 

Both PRP and PRF follow a similar process. A small amount of blood is drawn and processed to concentrate the platelets. The solution is then injected into the treatment area using a fine needle. A topical numbing cream is applied beforehand to ensure your comfort. 

The procedure takes about 60 minutes with little to no downtime. You may experience mild redness or swelling, but this usually resolves within a day or two. Results develop as your body responds to the growth factors. 

Multiple sessions may be suggested for optimal results, and Dr. Ho and Dr. Caruth will create a treatment plan based on your goals. 

Discover which treatment is right for you 

So how does PRP work, and what is PRF? If you have questions about these treatments for skin rejuvenation, advanced hair restoration, or as a collagen booster, Beyond Beautiful in Plano is here to help. Dr. Vu Ho and Dr. Jeffrey Caruth serve patients from McKinney, Frisco, Prosper, Solano, Allen, and Richardson, TX. Call for a consultation and find out which can help you achieve your goals.

Sarah was thorough, professional and kind. The atmosphere is relaxing and the med spa was spotless.

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I love Dr. Carruth and his staff! I’ve had a couple of procedures and have been very happy with the results! His staff always helps to ease my anxiety and make me feel very comfortable and he thoroughly explains the entire procedure and makes sure I understand. He truly cares about me and makes sure I’m 100% happy.

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Dr. Caruth cares about his patients . Been going for years and he never tries to sell you on anything. Always just wants to meet your needs

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Dr. Caruth and his staff are amazing. I highly recommend Dr. Caruth. He took exceptional care of me with my procedure. Hands down, an outstanding doctor!

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Xanthoma Removal from Upper Eyelids - Had these white sacs forming on my upper eyelids and discovered they were Xanthomas, a cholesterol deposit. Dr. Ho said he could remove them and lift the sagging eyelid in the process. The surgery went great and 4.5 months later, I'm fully healed. Highly recommend his work.

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* All information subject to change. Images may contain models. Individual results are not guaranteed and may vary.